q-bio.GN

Lingshu-Cell: A generative cellular world model for transcriptome modeling toward virtual cells

/ March 31, 2026

arXiv:2603.25240v1 Announce Type: cross
Abstract: Modeling cellular states and predicting their responses to perturbations are central challenges in computational biology and the development of virtual cells. Existing foundation models for single-cell…

cs.LG, q-bio.GN, stat.ML

A Large-Scale Comparative Analysis of Imputation Methods for Single-Cell RNA Sequencing Data

Yuichiro Iwashita, Ahtisham Fazeel Abbasi, Muhammad Nabeel Asim, Andreas Dengel / March 27, 2026

arXiv:2603.24626v1 Announce Type: cross
Abstract: Single-cell RNA sequencing (scRNA-seq) is inherently affected by sparsity caused by dropout events, in which expressed genes are recorded as zeros due to technical limitations. These artifacts distort …